Generic Name: Ofloxacin
Trade Name: Dizoflox
Manufacturer: Ashford Pharmaceutical Laboratories, Inc.
Source of Supply: Vendiz Pharmaceuticals Inc.
Pharmacologic Classification: Fluoroquinolone Eye Anti-infectives
Mechanism of Action: Ofloxacin has in vitro activity against a wide range of gram- negative and gram-positive microorganisms. Ofloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential bacterial enzyme which is a critical catalyst in the duplication, transcription, and repair of bacterial DNA.
Therapeutic Indication: It is indicated for the treatment of external eye infections such as blepharitis, hordeolum, dacryocystitis, conjunctivitis, meibomitis, keratitis, trachoma, and for the prevention of infection following corneal ulceration.
Dosage Forms & Strength: 3mg/mL (0.3%) Ophthalmic Solution
Dosage and Administration: Instill 1 to 2 drops twice daily for 7 days to a maximum of 2 weeks or as prescribed by the physician.
Adverse Reactions: Irritation and stinging effect
Contraindications: It is contraindicated in patients with a history of hypersensitivity to ofloxacin, to other quinolones, or to any of the components in this medication.
Storage Condition: Store at temperature not exceeding 300
Generic Name: Hypromellose
Trade Name: Hypromax
Manufacturer: Ashford Pharmaceutical Laboratories, Inc.
Source of Supply: Vendiz Pharmaceuticals Inc.
Pharmacologic Classification: Ophthalmic Lubricant
Mechanism of Action: It acts to stabilize and thicken the pre corneal tear film and prolong the tear film breakup time which is usually accelerated in patients with dry eye states. It also acts to lubricate and protect the eye. It usually reduces the signs and symptoms resulting from moderate to severe dry eye syndromes
Therapeutic Indication: Ophthalmic Lubricant
Dosage Forms & Strength: 3mg/mL (0.3%) Sterile Ophthalmic Solution
Dosage and Administration: Instill 1-2 drops in each eye. For contact lenses apply a few drops before insertion. Adverse Reactions: Eye discomfort/irritation/redness, tearing, temporary blurred vision.
Storage Condition: Protect from light. Store at temperature not exceeding 300 C.
Generic Name: Polymyxin B sulfate
Formulation: Neomycin sulfate Dexamethasone
Each ml contains: Polymyxin B sulfate – 6000 Units, Neomycin sulfate – 5 mg, Dexamethasone ( as Sodium Phosphate ) – 1 mg
Indication: Management of ocular infections and inflammations produced by organisms which are sensitive to Neomycin and Polymyxin B sulfate. Acute or chronic non-purulent conjunctivitis, kerato-conjunctivitis, nonspecific superficial keratitis, Herpes zoster ophthalmicus, mild acute iritis, iridocyclitis, corneal ulcer, non-purulent blepharitis, scleritis, post-operatively to prevent ocular infection.
Dosage: Instill 1 – 2 drops in the conjunctival sacs 4 – 6 times daily. Dosage may be reduced after 3 to 4 days when a satisfactory response has been obtained.
Contraindications: This eye drop is contraindicated in tuberculous, fungal and most viral lesions of the eyes. Also in those patients who have shown hypersensitivity to any of its components.
Warning: Contains Sodium Metabisulfite, a sulfite that may cause allergic-type reactions
including anaphylactic symptoms and life threatening or less severe asthmatic episodes in certain susceptible individuals.
Storage: Store below 250 C.
Maxoptic Eye Drops is a sterile, buffered, and isotonic solution.
Generic Name: Polymyxin B sulfate,
Formulation: Neomycin sulfate Gramicidin
Each ml contains: Polymyxin B sulfate 5,000 Units Neomycin sulfate 1,700 Units Gramicidin 25 Units
Classification: Eye Anti-infectives and Antiseptics
Indications: For the prophylaxis and treatment of externalbacterial infections of the eye including conjunctivitis, blepharitis, keratitis, corneal ulcers, styes, abrations and lacerations.
Dosage: Instill 1 – 2 drops 2 – 4 times daily. In acute infections, therapy may be repeated every 15 to 30 minutes until infection is controlled.
Contraindications: Hypersensitivity to any of the components of the Ophthalmic Solutions.
Storage: Store below 250 C. Protect from light.
Availability: Box of 12’s
Generic Name: Prednisolone Acetate
Trade Name: Venpred
Manufacturer: Ashford Pharmaceutical Laboratories, Inc.
Source of Supply: Vendiz Pharmaceuticals, Inc.
Pharmacologic Classification: Eye Corticosteroids
Mechanism of Action: Corticosteroids inhibit the inflammatory response to a variety of inciting agents and probably delay or slow healing. They inhibit the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation associated with inflammation.
There is no generally accepted explanation for the mechanism of action of ocular corticosteroids. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from the membrane phospholipids by phospholipase A2.
Therapeutic Indication: For steroid responsive inflammation and allergic ocular conditions, inflammatory keratitis and otherinflammatory disorders of the anterior segments of the globe.
Dosage Forms & Strength: 10mg/mL Ophthalmic Suspension
Dosage and Administration: One to two drops twice a day to four times a day or as prescribed by a physician.
Adverse Reactions: Increased intraocular pressure with optic nerve damage, visual field defects. Systemic side effects may occur with extensive use of steroids.
Contraindications: Acute superficial herpes simplex keratitis; systemic fungal infections; varicella; Hypersensitivity to prednisolone
Storage Condition: Store at temperatures not exceeding 300 C.
Contents: Lutein, Zeaxanthin, Zinc, Selenium, Omega-3 Fatty Acids, Vitamin A, B3, B12, C, & E
Trade Name: vitaCLEAR
Manufacturer: Ashford Pharmaceutical Laboratories, Inc.
Source of Supply: Vendiz Pharmaceuticals, Inc.
Pharmacologic Classification: Food Supplement